Vasotrate-60 OD

Vasotrate-60 OD

isosorbide mononitrate

Manufacturer:

Torrent

Distributor:

Torrent
Concise Prescribing Info
Contents
Isosorbide mononitrate
Indications/Uses
Prophylaxis of angina & as adjunct in CHF.
Dosage/Direction for Use
Initially, 30 mg (given as a single 30-mg tab or as ½ of 60-mg tab) or 60 mg (given as a single tab) once daily, then may be increased to 120 mg (given as a single 120-mg tab or as two 60-mg tab) once daily.
Administration
May be taken with or without food: Swallow whole w/ ½ glass liqd, do not chew/crush. Preferably taken in the morning upon arising.
Contraindications
Hypersensitivity or idiosyncratic reactions to isosorbide mononitrate, other nitrates or nitrites.
Special Precautions
Severe hypotension, vol-depleted patients or hypotensive; patients w/ MI or CHF; hypovolemia, marked anemia, heart failure due to obstruction (including constrictive pericarditis), raised intracranial pressure due to head trauma or cerebral hemorrhage; severe renal or hepatic impairment, hypothyroidism, malnutrition or hypothermia. May aggravate angina caused by hypertrophic cardiomyopathy. Daily headaches sometimes accompany during treatment. Lightheadedness on standing may be frequent in patients who consumed alcohol. Pregnancy & lactation.
Adverse Reactions
Flushing of the face, dizziness, tachycardia, throbbing headache. Large doses may cause vomiting, restlessness, blurred vision, hypotension, syncope & rarely cyanosis, methemoglobinemia, impairment of resp & bradycardia.
Drug Interactions
Additive vasodilating effects w/ other vasodilator & other drugs w/ hypotensive actions. Additive effects w/ alcohol. Marked symptomatic orthostatic hypotension w/ Ca-channel blockers & organic nitrates.
MIMS Class
Anti-Anginal Drugs
ATC Classification
C01DA14 - isosorbide mononitrate ; Belongs to the class of organic nitrate vasodilators. Used in the treatment of cardiac disease.
Presentation/Packing
Form
Vasotrate-60 OD SR tab 60 mg
Packing/Price
70's (P1,820/box)
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